Antacids do not affect the bioavailability of azithromycin, but reduce the maximum blood concentration of 30%, the preparation should therefore be taken at least one hour buy trenbolone enanthate before or two hours after administration of these drugs and food.
Azithromycin no effect the concentration of carbamazepine, didanosine, rifabutin in the blood of methylprednisolone when used together.
For parenteral administration, azithromycin does not affect the concentration of cimetidine, efavirenz, fluconazole, indinavir, midazolam, triazolam, trimethoprim / sulfamethoxazole in the blood when used together, but do not exclude the possibility of such interactions in the appointment of azithromycin for oral administration.
azithromycin has no effect on the pharmacokinetics of theophylline, but when coadministered with other macrolides theophylline concentration in plasma can be raised.
if necessary, the joint use with cyclosporin, it is recommended to control the content of cyclosporine in the blood. Despite the fact that information about the impact of azithromycin data on the change in the blood concentration of cyclosporine no other members of the macrolide class capable of changing its level in the blood plasma.
When coadministration of digoxin and azithromycin necessary to monitor digoxin levels in blood, as many macrolides enhance absorption of digoxin intestine, thereby increasing its concentration in the blood plasma.
the joint appointment of warfarin and azithromycin is recommended careful monitoring of the prothrombin time.
it has been found that co-administration of terfenadine and macrolide class of antibiotics causes arrhythmias and prolongation of buy trenbolone enanthateinterval. Based on the fact, we can not exclude the above-mentioned complications by sharing a terfenadine and azithromycin.
Because there is the possibility of inhibiting the enzyme azithromycin in parenteral form with a joint appointment with cyclosporine, terfenadine, ergot alkaloids, cisapride, pimozide, quinidine, astemizole and other drugs, which are metabolized with this enzyme, the possibility should be considered when assigning such interaction azithromycin for oral administration.
when co-administered azithromycin and zidovudine, azithromycin does not affect the pharmacokinetic parameters of AZT in the blood plasma or its renal excretion and its glucuronide metabolite. However, increasing the concentration of the active metabolite – phosphorylated mononuclear cells in peripheral blood vessels. The clinical significance of this fact is not clear.
In simultaneous reception of macrolides with ergotamine and dihydroergotamine possible manifestation of their toxic effect.
. Of He taken with food
in case of missing the dose, the missed dose should be taken as soon as possible, and the next -. With an interval of 24 hours
. It is necessary to observe a break of 2 hours, while the buy trenbolone enanthate use of antacids
after discontinuation of treatment hypersensitivity reactions in some patients may stored, which requires a specific therapy under the supervision of a physician.