Lowering blood pressure, bradycardia, tachycardia, a transient increase in blood pressure (observed shortly after receiving sumatriptan). Heart rate, transient trenbolone enanthate for sale changes of ischemic myocardial miokaola. spasm of the coronary arteries. Sometimes develops Raynaud’s syndrome.
From the gastrointestinal tract
Nausea, vomiting, ischemic colitis (but link these side effects with sumatriptan has not been established); dysphagia, abdominal discomfort.
On the part of the central nervous system and sensory organs
Dizziness, rarely seizures (in some cases they have been observed in patients with a history of seizures or in conditions predisposing to seizures, some patients predisposing factors have been identified).Sometimes after taking sumatriptan noted diplopia, flashing before the eyes, nystagmus, scotoma, reduced visual acuity. Very rarely develops partial transient loss of vision. However, it should be borne in mind that visual impairment may be associated with a migraine attack itself.
Ranging from cutaneous manifestations (rash, urticaria, pruritus, erythema) to rare cases of anaphylaxis.
From the laboratory parameters
Minor changes in the activity of “liver” transaminases.
Receiving sumatriptan oral dose of 400 mg did not cause any side effects other than those listed above.
In case of overdose should be observed for the patients’ condition for at least 10 hours and spend symptomatic therapy if necessary. No data on trenbolone enanthate for sale the effect of hemodialysis or peritoneal dialysis on plasma concentrations of sumatriptan.
Sumatriptan should be used only if the diagnosis of migraine is no doubt that when it should be used as soon as possible after the onset of a migraine attack, although it is equally effective when used at any stage of attack. It can not be used as a preventive measure.
As with other protivomigrenoznyh funds, the appointment of sumatriptan in patients with previously diagnosed with migraine or patients with atypical migraine is necessary to exclude other potentially serious neurological conditions. It should be noted that patients with migraine are at increased risk of certain cerebrovascular events (stroke or transient ischemic attack). Sumatriptan should not be administered to patients with suspected heart disease without prior examination in order to avoid cardiovascular disease. Such patients include postmenopausal women, men over the age of 40 years and patients with risk factors for coronary heart disease. Although the survey has not always possible to detect heart disease in some patients, in very rare cases, they develop side effects to the cardiovascular system. After receiving sumatriptan may experience transient intense pain and tightness in the chest, extending to the neck. If there is reason to believe that these symptoms are a manifestation of coronary heart disease, it is necessary to conduct appropriate diagnostic testing. Do not exceed the recommended dose of sumatriptan.
INTERACTION WITH OTHER DRUGS
There was no interaction with sumatriptan trenbolone enanthate for sale propranolol, flunarizine, pizotifenom and ethyl alcohol.
When concomitantly with ergotamine celebrated long vasospasm. Sumatriptan may be administered no earlier than 24 hours after administration of preparations containing ergotamine; Conversely, the preparations containing ergotamine, can be administered no sooner than 6 hours after administration of sumatriptan.
Perhaps the interaction between sumatriptan and inhibitors as well as sumatriptan and drugs from the group of selective inhibitors of serotonin reuptake . There are some reports about the weakness of the development, hyperreflexia and poor coordination in patients after administration of sumatriptan and drugs . In the case of co-administration of sumatriptan and should be closely monitored condition of the patient.